Analyzing the .ica file on the end device is an advanced option which gives you the complete picture of the XenApp session formation and/or connectivity to the sessions. Whenever, you need to analyze an application session that fails for particular users, you can have the .ica file saved locally for analysis.
However, by default the .ica files are saved locally in the browser cache and are removed upon session exit. To have the ica file saved locally specify the path where to save the .ics files in below registry path and set the following key to True.
C:>reg query "HKEY_LOCAL_MACHINESOFTWAREWow6432NodeCitrixICA ClientEngineConfigurationAdvancedModulesLogging" /v LogFile
HKEY_LOCAL_MACHINESOFTWAREWow6432NodeCitrixICA ClientEngineConfigurationAdvancedModulesLogging
LogFile REG_SZ C:temp
C:>
C:>reg query "HKEY_LOCAL_MACHINESOFTWAREWow6432NodeCitrixICA ClientEngineConfigurationAdvancedModulesLogging" /v LogICAFile
HKEY_LOCAL_MACHINESOFTWAREWow6432NodeCitrixICA ClientEngineConfigurationAdvancedModulesLogging
LogICAFile REG_SZ true
C:>
Reference: How to Save the Launch.ica File to a Client Computer